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Ancillary & Wellness · Tablet / Capsule
Anastrozole
Anastrozole is a nonsteroidal aromatase inhibitor studied extensively in hormone-receptor-positive breast cancer in postmenopausal women. It reduces estrogen synthesis rather than directly modulating the estrogen receptor. That distinction separates it from tamoxifen and clomiphene, even though these medicines all appear in discussions of estrogen-related biology and endocrine feedback.
COA · Batch reports
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Mechanism & research
- Mechanism
Aromatase, CYP19A1, converts androgen precursors into estrogens. After menopause, peripheral conversion is an important source of estrogen, providing the biological rationale for aromatase inhibition in estrogen-dependent tumors. Anastrozole inhibits this enzymatic step without the same mechanism as adrenal steroid-synthesis blockade. Lower estrogen also affects bone remodeling and other tissues, so biochemical suppression and tumor-related endpoints need separate assessment.
Specifications and prices per listed pack. USD.
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