Ancillary & Wellness · Tablet / Capsule
Mesterolone is a synthetic androgen derived from dihydrotestosterone, historically described in Proviron product information for androgen deficiency. It is a steroidal androgen receptor agonist, distinct from testosterone esters and from medicines that stimulate the body's own gonadotropin secretion.
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Androgen receptors are intracellular transcription factors. Ligand binding changes receptor conformation and regulates gene expression in androgen-responsive tissues. Mesterolone's reduced steroid A ring means that it does not follow testosterone's aromatization pathway to estradiol. That distinction describes metabolism; it does not make androgen exposure free of effects on reproductive organs, skin, hair or endocrine feedback.
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