Ancillary & Wellness · Tablet / Capsule
Vardenafil is a phosphodiesterase type 5 inhibitor studied for erectile dysfunction. Its pharmacology depends on cyclic GMP signaling in smooth muscle and does not make it a testosterone replacement or a fertility medicine. The reference tablet label distinguishes the parent molecule, its hydrochloride salt and the contributions of an active metabolite.
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During sexual stimulation, nitric oxide increases cyclic GMP production in erectile tissue. Vardenafil inhibits PDE5-mediated degradation, supporting smooth-muscle relaxation and blood inflow. Laboratory selectivity studies also compare PDE6, PDE1 and other phosphodiesterases because those enzymes have different tissue functions. Selectivity is a relative experimental measurement, not an assurance that effects are confined to one organ or that cardiovascular interactions cannot occur.
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